Technical Development

Technical Development (TD) at Biogen Idec takes molecules from the R&D stage and readies them for manufacturing as commercial product. TD consists of four main departments:

Process Biochemistry (PBC)

  • Process development encompassing all aspects pharmaceutical proteins purification (cell culture harvest, column chromatography, membrane separations, ultra- and nano-filtration)
  • Supporting process validation, technology transfer of purification processes into cGMP manufacturing
  • Providing on-the-floor support during manufacturing start-up runs

Cell Culture Development (CCD)

  • Processing development encompassing all aspects of cell culture manufacturing processes (cell line development and selection, media and feed optimization, reactor systems and their control and scale-up)
  • Supporting process validation, technology transfer of cell culture processes into the cGMP manufacturing
  • Providing on-the-floor support during manufacturing start up runs

Protein Pharmaceutical Development (PPD)

  • Developing and validating the formulations, container closure, devices, and fill/finish drug product manufacturing processes
  • Moving Research discoveries through the drug development process
  • Placing commercialized drug product into a patient's hand in an innovative, technically robust, economical, and convenient dosage form

Analytical Development (AD)

  • Developing analytical methods for product release and characterization
  • Performing analyses in support of cell line selection, process and formulation development, product characterization, stability assessments, process validation, and more
  • Authoring CMC sections of regulatory submissions

Technical Development has opportunities in Cambridge, MA and Research Triangle Park, NC.

For openings and detailed job descriptions, view all Technical Development opportunities.