Process Biochemistry (PBC)

• Process development encompassing all aspects pharmaceutical proteins purification (cell culture harvest, column chromatography, membrane separations, ultra- and nano-filtration)
• Supporting process validation, technology transfer of purification processes into cGMP manufacturing
• Providing on-the-floor support during manufacturing start-up runs

Cell Culture Development (CCD)

• Processing development encompassing all aspects of cell culture manufacturing processes (cell line development and selection, media and feed optimization, reactor systems and their control and scale-up)
• Supporting process validation, technology transfer of cell culture processes into the cGMP manufacturing
• Providing on-the-floor support during manufacturing start up runs

Protein Pharmaceutical Development (PPD)

• Developing and validating the formulations, container closure, devices, and fill/finish drug product manufacturing processes
• Moving Research discoveries through the drug development process
• Placing commercialized drug product into a patient's hand in an innovative, technically robust, economical, and convenient dosage form

Analytical Development (AD)

• Developing analytical methods for product release and characterization
• Performing analyses in support of cell line selection, process and formulation development, product characterization, stability assessments, process validation, and more
• Authoring CMC sections of regulatory submissions

Technical Development has opportunities in Cambridge, MA and Research Triangle Park, NC.

For openings and detailed job descriptions, view all Technical Development opportunities.